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Profhilo East Preston


At No.109 The Wellness Clinic, we provide an innovative skin remodelling treatment called Profhilo® that is specifically designed to rejuvenate ageing skin by stimulating the production of collagen and elastin, crucial proteins responsible for maintaining skin firmness, hydration, and repair. Profhilo® utilises hyaluronic acid (HA), a naturally occurring substance, to help diminish the appearance of fine lines, wrinkles and crepey skin texture. The cohesive nature of Profhilo means it spreads quickly in both the dermis and epidermis after injection, delivering consistent results that tighten and lift the skin by improving both skin tone and texture.

What we can help with

Sagging Skin Profhilo

Sagging skin

Elevate your skin's firmness and elasticity with Prohilo, as our revolutionary treatment targets sagging skin, promoting a lifted and rejuvenated appearance.

Profhilo Wrinkles


Gain a smoother, more youthful complexion with Prohilo's hyaluronic acid formulation, visibly reducing fine lines and wrinkles for a fresher, age-defying look.

Crepey Skin Profhilo

Crepey skin

Rejuvenate crepey skin and restore its supple texture with Prohilo's targeted hyaluronic acid delivery, leaving you with visibly firmer and tighter skin.

Dehydradtion Profhilo


Quench your skin's thirst with Prohilo's deep hydration, restoring moisture balance and leaving your skin radiant, plump, and revitalised.

Profhilo fine lines

Folds & lines

Effortlessly combat smile lines and marionette wrinkles with Prohilo's precision application, achieving a more youthful and refreshed appearance.

Dull Texture Profhilo

Dull texture

Say goodbye to dullness! Prohilo's transformative BAP technology revitalizes lackluster skin, unveiling a radiant and luminous complexion.

What is the treatment process?

You will be guided through an extensive consultation and consent process to ensure you understand the treatment. Numbing cream will be applied and after a period of about 30mins the treatment will begin with you lying down comfortably. Your face will be marked up strategically with the product injected in 5 defined points on each side of the face, dispersing across the entire mid and lower face. You will require a minimum of two treatments with a 4-week interval. Mature clients may require a third treatment for optimal results but this will be discussed on an individual basis. 

Benefits of No.109

Natural looking results

Profhilo delivers natural-looking results, enhancing the skin's overall appearance without an overly "done" or artificial look. It promotes a fresh, radiant, and rejuvenated complexion.



30 mins numbing cream 

30 mins procedure


6-12 months




£250 per treatment

2 x treatments required with 4 week interval


No. 109 Wellness Clinic

Q. Will it be painful? A. Numbing cream will be applied for 30mins before treatment which will reduce tenderness during the treatment. Clients describe a mild stinging and tightness. Post-treatment inflammation may occur, including mild bruising and swelling, so we advise to plan your appointment with sufficient time around any important date or event.

Q. Am I a suitable candidate for Profhilo? A. Profhilo is an advanced anti-ageing hydration treatment that effectively boosts moisture levels beneath the skin's surface and stimulates the natural synthesis of collagen and elastin. This remarkable treatment is suitable for individuals seeking enhanced hydration, increased collagen, and improved elastin levels. Although no upper age limit, the ideal candidates for Profhilo are typically aged between 30 and 65, who desire a more youthful appearance and wish to improve the overall condition of their skin. By harnessing the power of Profhilo, clients can achieve a revitalised and rejuvenated complexion. For clients with deep folds in the skin, alternative treatments may be better suited and this will be discussed during your consultation.

Q. How is Profhilo different from traditional dermal filler? A. Profhilo distinguishes itself from dermal fillers in its composition and mode of action. Dermal fillers typically add volume whilst Profhilo is primarily a hydrating treatment dispersed across the skin. While both contain hyaluronic acid, Profhilo differs in viscosity from dermal fillers. Rather than having a thick consistency, Profhilo is more purified form of Hyaluronic acid, with a gel-like substance similar to honey. It is delicately injected in small quantities across the face, where it spreads beneath the skin's surface. Profhilo is also the first hyaluronic acid product that does not contain chemical cross-linking agents like BDDE, making it a safe alternative with fewer unwanted side effects. This unique formulation stimulates collagen and elastin production, leading to improvements in skin tone, texture, and elasticity. The outcome is a more youthful, well-hydrated, and radiant complexion. Unlike dermal fillers that target specific lines or folds, Profhilo enhances entire areas. It has the ability to flow smoothly through the deeper layers of the skin, which dermal fillers typically cannot achieve. This characteristic of Profhilo minimises the risk of creating lumps or bumps. Additionally, Profhilo is particularly suitable for areas such as the neck and décolletage where dermal fillers are not commonly used. By utilising Profhilo in these areas, rejuvenation and enhancement can be achieved effectively for subtle, natural-looking results.

Q. When will I see results? A. Results from Profhilo do not appear immediately because its mechanism of action works by tissue stimulation. The product acts as a bio-rejuvenator and bio-revitaliser and requires time for the skin remodelling process to take place. The best results will appear 4-6 weeks after your second treatment. Clients can achieve remarkable results improving their complexion with a subtle, natural-looking radiance that typically last between 6-12 months. This may vary according to client age, skin condition and lifestyle

Q. What aftercare advice is there? A. There is no downtime necessary, and most patients can return to their usual routine immediately after treatment. However, clients should avoid wearing makeup, exposure to extreme temperatures, sunlight, swimming, exercise, and touching the site of injection for 24 hours post-treatment. Avoid using products containing retinoids, alpha hydroxy acids (AHAs), or beta hydroxy acids (BHAs) for a few days post-treatment, as they can cause irritation.

Q. What are the possible risks and side effects? A. Like any cosmetic procedure Profhilo can have mild temporary side effects. You will feel a stinging sensation on injection, and if you are concerned about the pain, we advise that as well as having the numbing cream you take two paracetamol tablets before your appointment providing you have no contraindications. Patients may experience lumps, redness, bruising and tenderness at the injection site, but this should subside within a day, often with 30 minutes. If you have specific concerns or conditions, be sure to discuss them with us. At 109 Clinic, your safety is our top priority and you can be confident our expert team will minimize the risks and side effects, providing you with a worry-free experience as well as stunning, rejuvenated skin.

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